Virucidal Activity of World Health Organization–Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses

نویسندگان

  • Anindya Siddharta
  • Stephanie Pfaender
  • Nathalie Jane Vielle
  • Ronald Dijkman
  • Martina Friesland
  • Britta Becker
  • Jaewon Yang
  • Michael Engelmann
  • Daniel Todt
  • Marc P. Windisch
  • Florian H. Brill
  • Joerg Steinmann
  • Jochen Steinmann
  • Stephan Becker
  • Marco P. Alves
  • Thomas Pietschmann
  • Markus Eickmann
  • Volker Thiel
  • Eike Steinmann
چکیده

The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations.

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عنوان ژورنال:

دوره 215  شماره 

صفحات  -

تاریخ انتشار 2017